When OpenAI quietly launched ChatGPT in late November 2022, no one at the company was prepared for the viral megahit. Inside the company, it was billed as a “research preview,” teasing a more polished version of the two-year-old technology and a way to fix some of its flaws.

But then it completely fell apart. Since then, the firm has been looking to catch up and capitalize on its success.

To get the inside story on the chatbot—how it was created, how OpenAI has updated it since its release, and how the creators feel about its success—our senior AI editor Will Douglas Haven spoke with four people who helped create what has become the most popular internet application.

— Will Douglas Haven

The idea of ​​using the “three parent” method to treat infertility has just received a boost

This week my colleague Jessica Hamzelow published a great story about a controversial treatment that creates children with three genetic parents. The “three parents” technique was believed to help parents avoid passing diseases to their children. But new findings suggest it doesn’t always work – and could be creating babies at risk of serious illnesses.

The evidence comes from two babies born after the procedure was used to help couples with another problem: infertility. Fortunately, we found the problem in these cases—these babies didn’t have parents with disease-causing mutations, so they should be fine.

And there is another silver lining. The findings add to the growing body of evidence that the three-parent method can help treat infertility and shed light on why some people struggle to conceive. Read the story in its entirety.

This is a story from The Checkup, Jessica’s weekly newsletter covering all kinds of biotech breakthroughs. Register to get it in your mailbox every Thursday.

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